Laboratory of Clinical Investigation, National Institute on Aging, Maryland, USA

Talk Title : Ligand fishing and bioaffinity chromatography for natural product screening

Ruin Moaddel obtained his Ph.D. at Northeastern University, followed by post-doctoral studies at Georgetown University, Washington D.C until 2001. His focus for the past few years has been on the development of ketamine metabolites for the treatment of depression and bioaffinity chromatography, including cellular membrane affinity chromatography for the identification of active components in complex matrices, including tobacco smoke condensates and on the development and application of protein-coated magnetic beads for ligand fishing. Specifically, focusing on the isolation and identification of biologically active secondary metabolites for SIRT6 protein.